"Don’t eat oranges before nucleic acid testing!"
"These acidic foods will make your nucleic acid positive!"
The saying that "eating oranges and other acidic foods can cause nucleic acid test results to be positive"
is this real?
The Internet passes "eating oranges will become positive"
is that true?
The reason why these claims appear
It is because some people do antigen detection at home orange juice
The results showed "two bars"
In the video
The operator directly squeeze the orange juice on the new crown antigen reagent test box
Later, there were purple -red horizontal lines appeared in the T and C areas
These contents cause many people to panic
Asked whether it is true or false
I even said I dare not eat oranges anymore
Some netizens also said
I often eat these fruits at home recently
None of the nucleic acid detection of myself and the family is not abnormal
Reporter randomly finds a nucleic acid test convenience service point
After eating oranges for about 2 minutes
And without drinking water and eating other foods
Participate in nucleic acid sampling
7 am on November 28th
The reporter opened Beijing Health treasure for nucleic acid self -examination
Results show: negative
Expert: Use orange juice for testing, the result is meaningless
Will eating oranges affect
Antigen detection and nucleic acid detection results?
Xu Hui, director of the Inspection Department of Emergency General Hospital, said
Sample detection is a "fine work"
The quality control of the full process needs to be performed
That is, before sampling, sampling, after sampling
Make sure the operation is accurate
In order to ensure the accuracy of the results
First of all
Antigen detection and nucleic acid detection are different
Antigen detection of protein on the shell of the virus
Use colloid gold fast test card
The nucleic acid detection of the nucleic acid inside the virus shell
Methods are usually real-time fluorescent quantitative amplification detection (RT-PCR)
Netizens use orange juice to test the virus antigen
Antigen detection or nucleic acid detection
To get accurate test results
Specification sampling is the most critical part
Applicable samples of the new coronary antigen kit
"Human nasal mucosal epithelial cell"
Drop orange juice as a sample into the kit
It does not meet the sampling criteria itself.
What kind of result is presented
Use orange juice to test antigen
Why is there a fake positive?
In fact, in 2021, German researchers have done similar experiments
Not just orange juice
Researchers will have a variety of beverages such as cola, Fanta, Red Bull, Vodka, whiskey, Bailan, soda and other drinks
Drip directly in the new crown antigen detection hole
After a period of time
There will be a positive T -line
But the nucleic acid detection of these beverages
No new crown virus was detected
"This is because the antigen detection test box can only be effective only under the correct use method. When performing antigen detection, you need to sample the swab and put it in a sample pipe containing the sample processing solution.Reagent board. Similarly, the researchers mix these beverages and sample processing solution before dripping into the sample holes for detection. The antigen detection will not have the result of the red line of the T area. "
The secret is in the sample processing solution
The principle of the new crown antigen testing the kit is simply speaking
It is to capture specific antigens through specific antibodies
But the combination of antigen antibodies
Need to maintain a proper pH value (pH)
The sample treatment solution contains a buffer system
It can ensure that the antigen antibody is combined under the appropriate pH value
Add orange juice or various beverages directly to the reagent plate
Destroy the appropriate pH environment
Non -specific results of antigen antibody
This has created false positives